2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13056
    SMND-309
    SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats.
    SMND-309
  • HY-133668
    Monoethyl phthalate
    Monoethyl phthalate is a metabolite of diethyl phthalate. Monoethyl phthalate acts as a urinary biomarker of phthalates exposure indicating the risks of thyroid cancer and benign nodule.
    Monoethyl phthalate
  • HY-G0014A
    Quetiapine sulfoxide dihydrochloride
    		99.27%
    Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.
    Quetiapine sulfoxide dihydrochloride
  • HY-G0004
    Acetaminophen metabolite 3-hydroxy-acetaminophen
    		99.76%
    3-hydroxy-acetaminophen is a metabolite of Acetaminophen, which is a pain medicine.
    Acetaminophen metabolite 3-hydroxy-acetaminophen
  • HY-119124
    Edoxaban M4
    		99.13%
    Edoxaban M4, an active metabolite of Edoxaban, shows reproducible, but concentration-dependent matrix effects. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor .
    Edoxaban M4
  • HY-131964
    Imidacloprid-urea
    		99.86%
    Imidacloprid-urea is a metabolite of Imidacloprid. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid-urea can occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment.
    Imidacloprid-urea
  • HY-N3059
    Pinostilbene
    		99.96%
    Pinostilbene (trans-Pinostilbene) is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells.
    Pinostilbene
  • HY-16445B
    CNDAC hydrochloride
    		99.59%
    CNDAC hydrochloride is a metabolite of the orally active agent Sapacitabine (HY-16445), and a nucleoside analog. CNDAC hydrochloride induces DNA damage and apoptosis.
    CNDAC hydrochloride
  • HY-B1348
    Dimethadione
    		99.93%
    Dimethadione is the primary metabolite of trimethadione. Dimethadione causes depression of neuromuscular transmission. Dimethadione primarily decreases transmitter release from the nerve terminal.
    Dimethadione
  • HY-116617
    15-Keto Travoprost
    		99.20%
    15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes.
    15-Keto Travoprost
  • HY-W012982
    3-Amino-2-oxazolidinone
    		≥98.0%
    3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo.
    3-Amino-2-oxazolidinone
  • HY-135392
    N-Desmethyl Pimavanserin
    		98.88%
    N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
    N-Desmethyl Pimavanserin
  • HY-135356
    m-Nifedipine
    		98.09%
    m-Nifedipine is an impurity of Nifedipine (BAY-a-1040). Nifedipine is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
    m-Nifedipine
  • HY-Y1771
    2-Carboxybenzaldehyde
    		99.95%
    2-Carboxybenzaldehyde is the major metabolite found in phenanthrene metabolism. Phenanthrene can be degrade by Pseudomonas sp. Lphe-2 strain.
    2-Carboxybenzaldehyde
  • HY-W008216
    HMMNI
    		99.76%
    HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections.
    HMMNI
  • HY-W017434
    3,4-Dimethylbenzoic acid
    		98.32%
    3,4-Dimethylbenzoic acid acts as a product of dimethylbenzoate metabolism by Rhodococcus rhodochrous N75.
    3,4-Dimethylbenzoic acid
  • HY-131669
    Dasatinib metabolite M6
    		99.64%
    Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib (HY-10181). Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor.
    Dasatinib metabolite M6
  • HY-N7781
    (-)-(E)-Guggulsterone
    		99.27%
    (-)-(E)-Guggulsterone is the metabolite of Z-guggulsterone. Guggulsterone is an active constituent of guggulipid, an ayurvedic agent derived from Commiphora mukul. Guggulsterone has hypolipidaemic activity.
    (-)-(E)-Guggulsterone
  • HY-148053
    Rezivertinib analogue 1
    		99.68%
    Rezivertinib analogue 1 is a process impurity of osimertinib mesylate. Rezivertinib analogue 1 can be used in the study of non-small cell lung cancer.
    Rezivertinib analogue 1
  • HY-B1398
    Ampyrone
    		99.25%
    Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.
    Ampyrone
Cat. No. Product Name / Synonyms Application Reactivity